Earlier guidelines such as the National Osteoporosis Foundation NOF selected patients for treatment who had pre-existing hip or spine fracture, or low BMD with clinical risk factors. It may depend on the intensity of accompanying interventions. J Bone Miner Res , The effect on FRAX on distal outcomes is less clear. A personal perspective on fracture risk assessment tools. Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds. The impact of the use of multiple risk indicators for fracture on case-finding strategies:

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The absolute risk of fracture refers to the individual risk of fractures over a certain time period [ 14 ]. Bone mineral density is a predictor of survival.

J Bone Miner Res.

FRAX | Osteoporosis Canada

If BMD is entered, secondary osteoporosis does not change the calculated risk. It is important to note that background risk of fracture in FRAX will vary between populations.

Print tool and information. Therefore, it is likely that providing global risk information to patients at only one point in time may well be relatively ineffective [ 60 ].

There have been no studies as yet to confirm whether the use of FRAX will improve outcomes. calcklator

frax calculator

Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX. If ages below or above are entered, the programme will compute probabilities at 40 and 90 year, respectively.



A previous fracture denotes more accurately a previous fracture in adult life occurring spontaneously, or a fracture arising from trauma which, in a healthy individual, would not have resulted in a fracture. With the increased recognition that over half of individuals in the community with fractures do not have osteoporosis as defined by BMD, we calcultaor separate patients with low bone mass into those with low risk versus high risk. However, this ratio may not apply across all racial and ethnic groups in countries and regions of the world.

This paper demonstrates alcohol intake as a risk factor for fracture independent of BMD.

The global cohort consisted of approximatelyperson dalculator, approximately 60, patients, and fractures. Bone mineral density BMD assessment, although specific, may not be sensitive for predicting fracture risk. J Bone Miner Res This article has been cited by other articles in PMC.

The Utility and Limitations of FRAX: A US Perspective

They are often only valid and include other additional factors that may not be included in FRAX such as falls. A meta-analysis of previous fracture and subsequent fracture risk. This paper explains how multiple risk factors can be integrated to improve the prediction of fracture risk. This paper demonstrates the importance of prior corticosteroid use as a risk factor for fracture independent of BMD.


Please review our privacy policy. A prior frxx vertebral fracture or a hip fracture is an especially strong risk factor. J Bone Joint Surg Br.

Calculation Tool

The prevalence of vertebral deformity in European men and women: Silverman and Andrew D. Risk factors for incident vertebral fractures in men and women: Cummings S, Melton L.

frax calculator

Smoking and fracture risk: Enter yes if the patient has a disorder strongly associated with osteoporosis. Risk factors in the WHO algorithm are required to frzx simple, responsive to therapies available, and have been studied in population cohorts [ 25 ].

The Utility and Limitations of FRAX: A US Perspective

FRAX does not account for individuals who have low lumbar T-score but with normal femoral neck [ 19 ]. A special situation pertains to a prior history of vertebral fracture.

Enter yes or no see also notes on risk factors. Furthermore, multiple risk factors account for secondary osteoporosis. There are no data to know if this is true for African Americans, Hispanics, and Asians [ 52 ].